Search results for " Male [Medical Subject Headings]"

showing 10 items of 523 documents

Ureteral realignment with combined access as a treatment of complete ureteral transection.

2019

Ureteral realignment using a ureteral stent can be an alternative treatment in cases of complete ureteral transection and may avoid the need for reconstructive surgery. The combined access can help the passage of the guidewire through the injured area and the threading of the urinary system of the patient. We present a case of a 38-year-old man with multiples abdominal surgeries, who underwent a complete ureteral section treated with ureteral realignment with combined access. The subsequent evolution was favourable, with resolution of the ureteral injury at the acute time, and without the presence of long-term obstruction. Although we must accept that the standard treatment of the complete …

AdultMalemedicine.medical_specialtyReconstructive surgeryUrologyUrinary systemmedicine.medical_treatmentAnastomosisUreteral realignmenturologic and male genital diseaseslcsh:RC870-923Ureteral injurymedicineHumansbusiness.industryurogenital systemStandard treatmentTreatment optionsStentlcsh:Diseases of the genitourinary system. UrologyAlternative treatmentfemale genital diseases and pregnancy complicationsSurgeryUreteral traumasurgical procedures operativeUrologic Surgical ProceduresUreterbusinessEndourologyUreteral transectionArchivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
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Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
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Left ventricular filling abnormalities and obesity-associated hypertension: relationship with overproduction of circulating transforming growth facto…

2005

This study has been designed to evaluate the relationship among transforming growth factor beta1 (TGFbeta1) and some measurements of diastolic function in a population of hypertensive subjects with normal left ventricular ejection fraction. We studied 67 hypertensive outpatients who according to their BMI levels were subdivided into three groups: lean (L), overweight (OW) and obese (OB) hypertensives (HT). Circulating TGFbeta1 and M- and B-mode echocardiography was determined. All hypertensives were further subgrouped, according to European Society of Cardiology Guidelines, into two subsets of patients with normal diastolic function or with diastolic dysfunction. Prevalence of left ventricu…

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaHeart VentriclesEnzyme-Linked Immunosorbent Assayobesity-associated hypertension; TGFb1; left ventricular hypertrophy; left ventricular diastolic functionLeft ventricular hypertrophyTransforming Growth Factor beta1Ventricular Dysfunction LeftDiastoleRisk FactorsTransforming Growth Factor betaVentricule gaucheInternal medicineInternal MedicinemedicineHumansObesityOverproductionAgedbusiness.industryStroke VolumeNutritional statusMiddle Agedmedicine.diseaseMyocardial ContractionSettore MED/11 - Malattie Dell'Apparato CardiovascolareObesityEndocrinologyEchocardiographyHypertensionAdult Aged Biological Markers/blood Diastole Echocardiography Enzyme-Linked Immunosorbent Assay Female Heart Ventricles/physiopathology Heart Ventricles/ultrasonography Humans Hypertension/blood Hypertension/complications* Hypertension/physiopathology Hypertrophy Left Ventricular/blood Hypertrophy Left Ventricular/complications* Hypertrophy Left Ventricular/physiopathology Male Middle Aged Myocardial Contraction/physiology* Obesity/blood Obesity/complications* Obesity/physiopathology Regression Analysis Risk FactorsCardiologyRegression AnalysisFemaleHypertrophy Left VentricularbusinessVentricular fillingBiomarkersTransforming growth factorJournal of Human Hypertension
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Sulodexide versus calcium heparin in the medium-term treatment of deep vein thrombosis of the lower limbs.

1997

Thirty adult patients with distal, monolateral deep vein thrombosis of the lower limbs were randomly treated for sixty days either with subcutaneous Ca-Heparin or with Sulodexide, administered IM for ten days and orally for fifty days. The thrombus accretion above the knee, the venous pressures of the affected leg, the clinical sympto matology, and some laboratory coagulative tests were monitored throughout the admin istration period. Local tolerability of the two treatments was also evaluated.The two applied treatments evidenced a net antithrombotic activity, preventing thrombus accretion above the knee, improving with the same efficacy the venous pressures in the affected legs, and simila…

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina Internamedicine.drug_classDeep vein030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineFibrinolytic AgentsHumansMedicine030212 general & internal medicineThrombusAgedGlycosaminoglycansmedicine.diagnostic_testHeparinbusiness.industryAnticoagulantHeparinMiddle AgedThrombophlebitismedicine.diseaseThrombosisSulodexideSurgerymedicine.anatomical_structureTolerabilityAnesthesiaSettore BIO/14 - FarmacologiaFemaleAdult Aged Female Fibrinolytic Agents/administration & dosage Fibrinolytic Agents/therapeutic use* Glycosaminoglycans/administration & dosage Glycosaminoglycans/therapeutic use* Heparin/therapeutic use* Humans Male Middle Aged Thrombophlebitis/drug therapy*Cardiology and Cardiovascular Medicinebusinessmedicine.drugPartial thromboplastin time
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Colonic Conduit in Children

1996

Complication rates of up to 86.6% have been reported after creation of an ileal conduit. In contrast to others, we construct an antirefluxing isoperistaltic colonic for incontinent diversion in children.Between 1968 and 1989 a colonic conduit was created in 105 patients up to age 20 years for neurogenic bladder (76), bladder exstrophy (16) and other reasons (13). Long-term followup (minimum 5 years, mean 16.3 years, range 5 to 26) was possible in 84 patients (159 renal units).Early and late stenosis at the ureterocolic anastomosis, and stomal stenosis occurred in 7.6 and 15.5% of the cases, respectively. Renal calculi developed in 8.2% of the renal units. Eight kidneys without function afte…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentColonUrologyUrinary Diversionurologic and male genital diseasesStomal stenosisPostoperative ComplicationsRecurrent pyelonephritisHumansMedicineChildUpper urinary tractbusiness.industryUrinary Bladder DiseasesInfantColonic conduitUreterocolic anastomosismedicine.diseaseSurgeryBladder exstrophyStenosisChild PreschoolFemalebusinessComplicationFollow-Up StudiesThe Journal of Urology
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Long-term urinary dysfunction after mesorectal excision: a prospective study with intraoperative electrophysiological confirmation of nerve preservat…

2006

Bladder dysfunctions are well-recognized complications after nerve-sparing mesorectal excision for rectal cancer. This study sought to symptomatically analyze the extent of recovery from major and minor urinary symptoms in patients with signs of bladder denervation.Sixty-two patients with mesorectal excision for rectal cancer were investigated prospectively. Pelvic autonomic nerve preservation (PANP) was assessed macroscopically and with the aid of intraoperative electrical stimulation of pelvic autonomic nerves (INS). Bladder function was evaluated with the International Prostate Symptom Score (IPSS) and the Quality of life index (Qol). Median follow-up was 20 months (range 3-40 months).Fo…

AdultMalemedicine.medical_specialtyUrinary systemUrinary BladderElectric Stimulation Therapyurologic and male genital diseasesQuality of lifeParasympathetic Nervous SystemMonitoring IntraoperativemedicineHumansProspective StudiesProspective cohort studyNeurogenic bladder dysfunctionMesorectalAgedAged 80 and overbusiness.industryRectal NeoplasmsRectumGeneral MedicineMiddle AgedUrinary functionmedicine.diseaseSurgeryTreatment OutcomeUrinary IncontinenceOncologyQuality of LifeSurgeryInternational Prostate Symptom ScoreFemaleComplicationbusinessFollow-Up StudiesEuropean journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
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Transposition of the left renal vein for treatment of the nutcracker phenomenon: long-term follow-up

2002

Abstract Objectives To assess the therapeutic value of left renal vein transposition for treatment of the nutcracker phenomenon in long-term follow-up. Methods Eight patients (4 women and 4 men) between 23 and 58 years old (mean 39.1) underwent transposition of the left renal vein for treatment of the nutcracker phenomenon associated with recurrent gross hematuria and flank pain. The postoperative follow-up was 41 to 136 months (mean 66.4). Results No perioperative complications were encountered. The postoperative complications comprised deep vein thrombosis (n = 1), retroperitoneal hematoma necessitating surgical revision (n = 1), and paralytic ileus that resolved with conservative managem…

AdultMalemedicine.medical_specialtyUrologyDeep veinmedicine.medical_treatmentPainConstriction Pathologicurologic and male genital diseasesInferior vena cavaRenal VeinsNutcracker syndromeMesenteric Artery SuperiorRecurrenceLaparotomymedicineHumansHematuriabusiness.industryRenal Nutcracker SyndromeSyndromePerioperativeMiddle Agedmedicine.diseaseThrombosisSurgeryRadiographyTreatment Outcomemedicine.anatomical_structuremedicine.veinFemalebusinessVascular Surgical ProceduresFollow-Up StudiesKidney diseaseUrology
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Retroaortic left renal vein joining the left common iliac vein

2000

Retroaortic left renal vein joining the left common iliac vein is a rare congenital anomaly in the development of the inferior vena cava. To our knowledge, only one case has been reported in the literature; however, its imaging features have never been described. A 27-year-old male presented with a 1-year history of recurrent right flank pain, dysuria, hematuria, and fever (39 degrees C). Computed tomography and MR venography showed a retroaortic left renal vein joining the left common iliac vein. We present the CT and MR venography findings and discuss their feasibility in showing this congenital anomaly.

AdultMalemedicine.medical_specialtyVena Cava InferiorIliac Veinurologic and male genital diseasesInferior vena cavaRenal VeinsMagnetic resonance angiographyImaging Three-DimensionalmedicineLeft common iliac veinHumansDysuriaRadiology Nuclear Medicine and imagingNeuroradiologyKidneymedicine.diagnostic_testbusiness.industryLeft renal veinInterventional radiologyGeneral MedicineAnatomymedicine.anatomical_structuremedicine.veincardiovascular systemRadiologymedicine.symptomTomography X-Ray ComputedbusinessMagnetic Resonance AngiographyEuropean Radiology
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A multicenter clinical trial on the use of alpha1-antichymotrypsin-prostate-specific antigen in prostate cancer diagnosis

2001

BACKGROUND The aim was to evaluate the clinical performance of alpha1-antichymotrypsin prostate-specific antigen (PSA-ACT) for early diagnosis of prostate cancer (PCa) in a multicenter trial. METHODS Three hundred sixty-seven white men with PCa and 290 with benign prostatic hyperplasia (BPH) with tPSA concentrations between 2 and 20 μg/L were analyzed. The Elecsys system 2010 (Roche Diagnostics, Germany) was used for determination of total PSA (tPSA) and free PSA (fPSA). The PSA-ACT test was a prototype assay used on the ES system (Roche Diagnostics). RESULTS The median concentrations of tPSA (PCa: 8.43 μg/L vs. BPH: 6.60 μg/L) and PSA-ACT (8.30 μg/L vs. 6.46 μg/L) were significantly differ…

AdultMalemedicine.medical_specialtyalpha 1-AntichymotrypsinUrologyProstatic HyperplasiaUrologyEnzyme-Linked Immunosorbent Assayurologic and male genital diseasesStatistics NonparametricProstate cancerProstateMulticenter trialmedicineHumansProtease InhibitorsAlpha1 AntichymotrypsinAgedAged 80 and overGynecologyReceiver operating characteristicbusiness.industryArea under the curveAntibodies MonoclonalProstatic NeoplasmsMiddle AgedProstate-Specific Antigenmedicine.diseaseClinical trialProstate-specific antigenmedicine.anatomical_structureROC CurveOncologybusinessThe Prostate
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Clinical correlates of renal dysfunction in hypertensive patients without cardiovascular complications: the REDHY study

2009

Our study was aimed to assess the clinical correlates of different degrees of renal dysfunction in a wide group of non-diabetic hypertensive patients, free from cardiovascular (CV) complications and known renal diseases, participating to the REDHY (REnal Dysfunction in HYpertension) study. A total of 1856 hypertensive subjects (mean age: 47+/-14 years), attending our hypertension centre, were evaluated. The glomerular filtration rate (GFR) was estimated by the simplified Modification of Diet in Renal Disease Study prediction equation. A 24-h urine sample was collected to determine albumin excretion rate (AER). Albuminuria was defined as an AER greater than 20 mug min(-1). We used the classi…

AdultMalemedicine.medical_specialtyarterial hypertensionWaistestimated glomerular filtration rateRenal functionDiseaseurologic and male genital diseasesalbuminuriaRisk FactorsInternal medicinerenal dysfunctionInternal MedicinemedicineHumansAgedKidneybusiness.industryMiddle Agedmedicine.diseasefemale genital diseases and pregnancy complicationsmedicine.anatomical_structureBlood pressureEndocrinologyLogistic ModelsCardiovascular DiseasesChronic DiseaseHypertensionCardiologyAlbuminuriaOriginal ArticleFemaleKidney Diseasesmedicine.symptomComplicationbusinessKidney diseaseGlomerular Filtration RateJournal of Human Hypertension
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